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BMS684 Special Topics In Biotechnology UITM Assignment Sample Malaysia

BMS684 Special Topics in Biotechnology at UITM, Malaysia, is a course that enables students to apply their acquired knowledge and skills in evaluating and analyzing biotechnology-based products, services, or solutions. 

The BMS684  course adopts a distance learning approach, where students engage in literature surveys, self-reading, and scientific analysis, while also interacting with assigned lecturers. Emphasizing market strategies and requirements, students develop proposals for biotechnological solutions to real-life problems and present them. Additionally, students attend two seminars/conferences and produce independent written summaries as part of the course

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 Assignment Task 1 : Summarize core points from selected scientific articles on a biotechnology innovation/ application.

For Task 1, I have summarized the core points from two selected scientific articles on a biotechnology innovation/application: CRISPR-Cas9 gene editing and its application in agriculture.

Article 1: CRISPR-Cas9 Gene Editing for Therapeutic Applications

  • CRISPR-Cas9 is a revolutionary gene-editing tool that enables precise modifications in the DNA of organisms.
  • The system consists of two components: the Cas9 enzyme, which acts as molecular scissors, and a guide RNA that directs Cas9 to the target gene.
  • The technology has been used in various therapeutic applications, such as correcting genetic mutations in human cells to treat hereditary diseases.
  • Researchers have explored its potential in cancer treatment by disabling oncogenes or activating tumor suppressor genes.
  • Ethical concerns surround its use in germline editing, as altering genes in human embryos can have unknown consequences for future generations.

Article 2: CRISPR-Cas9 in Agriculture: Transforming Crop Improvement

  • CRISPR-Cas9 has shown promising applications in agriculture for crop improvement.
  • It allows precise editing of plant genomes, leading to enhanced crop yield, nutritional content, and resistance to diseases and pests.
  • Researchers have successfully modified genes in major crops like rice, wheat, and maize to improve their agronomic traits.
  • The technology also enables reducing dependency on chemical pesticides and fertilizers, promoting sustainable agriculture practices.
  • Regulatory challenges and public acceptance remain significant hurdles for the adoption of CRISPR-edited crops.

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Assignment Task 2 : Evaluate the impact of the biotechnology innovation/ applications, including limitations and possible improvements

CRISPR-Cas9 Gene Editing: 

Impact:

  • CRISPR-Cas9 has revolutionized gene editing, allowing targeted modifications in various organisms, including humans and plants.
  • In therapeutic applications, it holds tremendous potential for treating genetic disorders and potentially eradicating some diseases.
  • In agriculture, CRISPR-Cas9 offers a sustainable and precise method for crop improvement, leading to increased food production and nutrition.

Limitations:

  • Off-target effects: CRISPR-Cas9 may introduce unintended mutations at sites other than the intended target, raising safety concerns.
  • Ethical dilemmas: The ethical implications of human germline editing and potential unintended consequences remain a contentious issue.
  • Delivery challenges: Efficient and safe delivery of CRISPR components to target cells remains a challenge, particularly in medical applications.

Possible Improvements:

  • Ongoing research focuses on improving the specificity of CRISPR-Cas9 to reduce off-target effects.
  • The development of alternative CRISPR systems, such as base editors and prime editors, may offer higher precision.
  • Addressing ethical concerns through robust regulatory frameworks and public engagement can help navigate the ethical complexities.

Assignment Task 3  : Demonstrate inquisitive mind skills in scientific /entrepreneurial activities/ seminars/ conference

During scientific seminars and conferences, I actively engage with experts and speakers by asking thoughtful questions that delve into the core aspects of their research or innovations. I express curiosity about the methodologies employed, potential limitations, and how their findings can be practically applied. I seek clarification on complex concepts and explore the broader implications of their work.

In entrepreneurial activities, I demonstrate an inquisitive mind by constantly seeking opportunities for innovation and improvement. I conduct market research to understand customer needs and pain points, asking critical questions to identify gaps in existing solutions. I stay updated with the latest advancements in biotechnology and related fields, seeking inspiration from cutting-edge research to develop novel and impactful products or services.

Overall, my inquisitive mind drives me to approach scientific and entrepreneurial endeavors with an open and exploratory mindset, always seeking to uncover new knowledge and solutions.

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